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1

Checkpoint Kinase Inhibitors: SAR and Radioprotective Properties of a Series of 2-Arylbenzimidazoles

Arienti, Kristen L., Brunmark, Anders, Axe, Frank U., McClure, Kelly, Lee, Alice, Blevitt, Jon, Neff, Danielle K., Huang, Liming, Crawford, Shelby, Pandit, Chennagiri R., Karlsson, Lars, Breitenbucher

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 408 KB

english, 2005

2

Phosphoinositide 3-Kinase Gamma (PI3Kγ) Inhibitors for the Treatment of Inflammation and Autoimmune Disease

Venable, Jennifer, Ameriks, Michael, Blevitt, Jonathan, Thurmond, Robin, Fung-Leung, Wai-Ping

Journal:

Recent Patents on Inflammation & Allergy Drug Discovery

Year:

2010

File:

PDF, 294 KB

2010

3

Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein–Protein Interaction

Blevitt, Jonathan M., Hack, Michael D., Herman, Krystal L., Jackson, Paul F., Krawczuk, Paul J., Lebsack, Alec D., Liu, Annie X., Mirzadegan, Taraneh, Nelen, Marina I., Patrick, Aaron N., Steinbacher,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.19 MB

english, 2017

4

Dual binding site inhibitors of B-RAF kinase

Ronald L. Wolin, Scott D. Bembenek, Jianmei Wei, Shelby Crawford, Katherine Lundeen, Anders Brunmark, Lars Karlsson, James P. Edwards, Jonathan M. Blevitt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

5

Phenotyping drug polypharmacology via eicosanoid profiling of blood

Song, Jiao, Liu, Xuejun, Rao, Tadimeti S., Chang, Leon, Meehan, Michael J., Blevitt, Jonathan M., Wu, Jiejun, Dorrestein, Pieter C., Milla, Marcos E.

Journal:

The Journal of Lipid Research

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

6

A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood

Song, Jiao, Liu, Xuejun, Wu, Jiejun, Meehan, Michael J., Blevitt, Jonathan M., Dorrestein, Pieter C., Milla, Marcos E.

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

7

Novel non-benzimidazole chk2 kinase inhibitors

Kelly J. McClure, Liming Huang, Kristen L. Arienti, Frank U. Axe, Anders Brunmark, Jon Blevitt, J. Guy Breitenbucher

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 171 KB

english, 2006

8

Concept and progress in the development of RGD-containmg peptide pharmaceuticals

William S. Craig, Soan Cheng, Daniel G. Mullen, Jon Blevitt, Michael D. Pierschbacher

Journal:

Year:

1995

Language:

english

File:

PDF, 106 KB

english, 1995

9

Design and operation of a 5000 m3/d reverse osmosis dual product plant

R. Blevitt, J.L. Hooper

Journal:

Year:

1977

Language:

english

File:

PDF, 1.37 MB

english, 1977

10

Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform

Song, J., Liu, X., Zhu, J., Tootoonchi, M., Keith, J. M., Meduna, S. P., Dvorak, C. A., Eccles, W., Krawczuk, P. J., Blevitt, J. M., Wu, J., Rao, N. L., Lebsack, A. D., Milla, M. E.

Journal:

Journal of Biomolecular Screening

Year:

2015

Language:

english

File:

PDF, 705 KB

english, 2015

11

p55CDC25is a Nuclear Protein Required for the Initiation of Mitosis in Human Cells

Jonathan B. A. Millar, Jonathan Blevitt, Larry Gerace, Krishna Sadhu, Carol Featherstone and Paul Russell

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.25 MB

english, 1991

12

A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo

Kenneth R. LaMontagne, Jeannene Butler, Virna B. Borowski, Angel R. Fuentes-Pesquera, Jonathan M. Blevitt, Shenlin Huang, Ronghua Li, Peter J. Connolly, Lee M. Greenberger

Journal:

Year:

2009

Language:

english

File:

PDF, 432 KB

english, 2009

13

p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

Millar, J. B., Blevitt, J., Gerace, L., Sadhu, K., Featherstone, C., Russell, P.

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.45 MB

english, 1991

14

2-Aryl benzimidazoles featuring alkyl-linked pendant alcohols and amines as inhibitors of checkpoint kinase Chk2

Danielle K. Neff, Alice Lee-Dutra, Jonathan M. Blevitt, Frank U. Axe, Michael D. Hack, Johnathan C. Buma, Raymond Rynberg, Anders Brunmark, Lars Karlsson, J. Guy Breitenbucher

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 191 KB

english, 2007

15

Identification of benzofuran central cores for the inhibition of leukotriene A4 hydrolase

Eccles, Wendy, Blevitt, Jonathan M., Booker, Jamila N., Chrovian, Christa C., Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M., Grice, Cheryl A., Herman, Krystal, Karlsson, Lars, K

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

16

Concept and progress in the development of RGD-containing peptide pharmaceuticals

William S. Craig, Soan Cheng, Daniel G. Mullen, Jon Blevitt, Michael D. Pierschbacher

Journal:

Year:

1995

Language:

english

File:

PDF, 1.61 MB

english, 1995

17

Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex.

Guan, T., Muller, S., Klier, G., Pante, N., Blevitt, J. M., Haner, M., Paschal, B., Aebi, U., Gerace, L.

Journal:

Molecular Biology of the Cell

Year:

1995

Language:

english

File:

PDF, 4.33 MB

english, 1995

18

Cloning and Pharmacological Characterization of a Fourth Histamine Receptor (H 4 ) Expressed in Bone Marrow

Liu, Changlu, Ma, Xiao-Jun, Jiang, Xiaoxia, Wilson, Sandy J., Hofstra, Claudia L., Blevitt, Jonathan, Pyati, Jayashree, Li, Xiaobing, Chai, Wenying, Carruthers, Nicholas, Lovenberg, Timothy W.

Journal:

Molecular Pharmacology

Year:

2001

Language:

english

File:

PDF, 210 KB

english, 2001

19

The alpha-helical rod domain of human lamins A and C contains a chromatin binding site.

Glass, C.A., Glass, J.R., Taniura, H., Hasel, K.W., Blevitt, J.M., Gerace, L.

Journal:

The EMBO Journal

Year:

1993

File:

PDF, 3.87 MB

1993

20

O-Linked Glycoproteins of the Nuclear Pore Complex Interact with a Cytosolic Factor Required for Nuclear Protein Import

Rachel Sterne-Marr, Jonathan M. Blevitt and Larry Gerace

Journal:

The Journal of Cell Biology

Year:

1992

Language:

english

File:

PDF, 2.61 MB

english, 1992

21

A Fluorescence-Based High Throughput Screen for the Transporter Associated with Antigen Processing

Journal:

Journal of Biomolecular Screening

Year:

1999

File:

PDF, 839 KB

1999

22

Cell Attachment and Motility on Materials Modified by Surface-active RGD-containing Peptides

JIM GLASS, JON BLEVITT, KEN DICKERSON, MICHAEL PIERSCHBACHER, WILLIAM S. CRAIG

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.15 MB

english, 1994

23

Phosphoinositide 3-Kinase Gamma (PI3Kγ) Inhibitors for the Treatment of Inflammation and Autoimmune Disease

Venable, Jennifer, Ameriks, Michael, Blevitt, Jonathan, Thurmond, Robin, Fung-Leung, Wai-Ping

Journal:

Recent Patents on Inflammation & Allergy Drug Discovery

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

24

Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist

Myagmar, Bat-Erdene, Ismaili, Taylor, Swigart, Philip, Raghunathan, Anaha, Baker, Anthony, Sahdeo, Sunil, Blevitt, Jonathan, Milla, Marcos, Simpson, Paul

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2018

Language:

english

File:

PDF, 52 KB

english, 2018

25

A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker

Crawford, S., Belajic, D., Wei, J., Riley, J. P., Dunford, P. J., Bembenek, S., Fourie, A., Edwards, J. P., Karlsson, L., Brunmark, A., Wolin, R. L., Blevitt, J. M.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 416 KB

english, 2008

26

Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist

Myagmar, Bat-Erdene, Ismaili, Taylor, Swigart, Philip, Raghunathan, Anaha, Baker, Anthony J, Sahdeo, Sunil, Blevitt, Jonathan M, Milla, Marcos E, Simpson, Paul C

Journal:

Circulation Research

Year:

2019

Language:

english

File:

PDF, 1.52 MB

english, 2019

27

Azabenzthiazole inhibitors of leukotriene A4 hydrolase

Tanis, Virginia M., Bacani, Genesis M., Blevitt, Jonathan M., Chrovian, Christa C., Crawford, Shelby, De Leon, Aimee, Fourie, Anne M., Gomez, Laurent, Grice, Cheryl A., Herman, Krystal, Kearney, Aaron

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.90 MB

english, 2012

28

A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors

Blevitt, Jonathan M., Hack, Michael D., Herman, Krystal, Chang, Leon, Keith, John M., Mirzadegan, Tara, Rao, Navin L., Lebsack, Alec D., Milla, Marcos E.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.58 MB

english, 2016

29

Letters. Beyond Acid Rain

Blevitt, Robert.

Journal:

Environmental Science & Technology

Year:

1987

Language:

english

File:

PDF, 808 KB

english, 1987

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